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Author Topic: HRT and dementia
skdadl
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posted 28 May 2003 10:45 AM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
The Journal of the American Medical Association (JAMA) has today published results of a study showing that post-menopausal women who take hormone-replacement therapy have twice the risk of developing Alzheimer's/dementia as those who do not.

(For some reason, the Globe and Mail site now crashes my computer when I try to go there. [But I'm not paranoid, noooo ...] Could someone who can still go there please post a link to the article in today's edition, by-line Andre Picard, p A14 in the print edition? Thanks.)

This study follows the initial findings of the Women's Health Initiative, released last year, which showed increased risk of breast cancer from HRT. (I will look later for the thread we wrote last year about that news, and add a link here.)


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sophrosyne
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posted 28 May 2003 11:35 AM      Profile for sophrosyne     Send New Private Message      Edit/Delete Post  Reply With Quote 
http://tinyurl.com/cuvx

I read this article with concern as well. When it's a decent hour I'm calling my Mom.


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lagatta
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posted 28 May 2003 11:53 AM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
Thanks sophrosyne.

I do suspect your mum is old enough to make her own decisions, though.


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skdadl
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posted 28 May 2003 01:32 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
Here is last summer's discussion about women's health concerns over HRT.

lagatta, one of the reasons I am so sensitive to this topic is that I spent a good decade listening to heavy propaganda -- from doctors and friends both -- in favour of HRT, as I suspect sophrosyne's mum did as well.

Sure, we can think for ourselves. But I tell you, it can be hard to stand up to the kind of concerted campaign that older women have faced on this turf.

For years, all I had to hang on to in my resistance to HRT was a vague feeling that menopause was not a disease and therefore shouldn't be hyped as such. I was amazed for years at the intense emotional reaction I got from family and friends for saying that out loud. Some of my relatives still won't discuss HRT with me -- and I have a feeling that this study is just going to make that worse.

Look at the reaction that the preliminary study got even from doctors! It is really hard for some people to give up something they believed in so hard -- which, of course, makes me wonder why so many believed so hard. What were they believing in? And why did it matter so much?


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lagatta
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posted 28 May 2003 01:40 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
Oh, skdadl, of course I've got that, and my friends a bit older than I am (your age) even more. It is just that, like you no doubt, I don't like people, including adult children, talking down to post-menopausal women (or to men of that age).

I think it is so hard to give up something that gave us a bit of hope to hang on to some benefits of youth and hold off the ravages of old age for a while, at least. That is merely human and normal.


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'lance
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posted 28 May 2003 01:47 PM      Profile for 'lance     Send New Private Message      Edit/Delete Post  Reply With Quote 
My mother's doctor suggested HRT to her a couple of years ago. Relating this, my mother -- a retired nurse, who knows from doctors and their enthusiasms -- got roughly the same kind of you've-got-to-be-kidding expression she might have had the quack suggested, say, leeches or blood-letting.

Quack's view was, well, it'll help bone density. Prevent osteoporosis, don't you know. The old gril had a couple of tests done and found out that her bone density, already nothing to worry about, actually increased measurably during the year or so the quack was occasionally suggesting this.

Curiously, the quack is female, and a generation or so younger than the old gril. I don't know what if anything any of this signifies, except maybe that some surprising people can get caught up in those weird beliefs tenuously held by an influential group.

[ 28 May 2003: Message edited by: 'lance ]


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skdadl
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posted 28 May 2003 02:20 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
I will confess one thing: my mum, who is eighty-nine and in many ways sharper than I, has been taking Premarin for I don't know how many years, and yet -- well, she is eighty-nine!

Mind you, it did nothing for her bones, which I believe was the point. To me, discovering at, say, age eighty that your joints are stiff and your bones more fragile than they used to be is just, y'know, life. To others, it seems something to be fought even harder with a medication that is CLEARLY NOT WORKING!

And then think of all those horses!


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sophrosyne
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posted 28 May 2003 02:46 PM      Profile for sophrosyne     Send New Private Message      Edit/Delete Post  Reply With Quote 
lagatta how do you feel justified making an assumption that I'd be "talking down" to my Mom? That's rather offensive - and a mighty strange assumption to make might I add. I wonder where you got the idea that talking with one's parents about their health would be in any way "talking down" to them. ??

FYI, I'm not going to tell my Mom to do anything, I wouldn't even dare... Rather, it usually works the other way around, with a "I told you so!"

[ 28 May 2003: Message edited by: sophrosyne ]


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lagatta
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posted 28 May 2003 02:47 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
The BBC also has an article on the study, which deals only with a specific type of HRT.

Certainly agree that conventional medicine tends to overmedicate for both physical and mental/emotional health complaints. But a friend who is a doctor (in a speciality other than gyno) is VERY leery of scare stories in the press. They are often simplistic.

Just thinking, skdadl. You put this topic in feminism, because it pertains to women's health, I surmise? I would have posted such health issues in body and soul.

By the way, there is no systematic equivalent of HRT for men of the equivalent age, but an uncle of mine was prescribed testosterone for a minor health complaint. This was the probable cause of his developing prostate cancer, according to his physician. My uncle is free of the cancer now, but the therapy left him with other rather serious health problems.


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Mandos
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posted 28 May 2003 02:50 PM      Profile for Mandos   Author's Homepage     Send New Private Message      Edit/Delete Post  Reply With Quote 
Oh, well. One day or another we'll find the fountain of youth in pill form.
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skdadl
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posted 28 May 2003 02:53 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
lagatta, I put it here because I really wanted women to see it! The thread last year was here, so ... Body and Soul is often a lot of fun ... but it is sometimes taken over, y'know, by ... ok: I won't mention the Guy threads, but ...
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Timebandit
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posted 28 May 2003 02:58 PM      Profile for Timebandit     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Oh, well. One day or another we'll find the fountain of youth in pill form.

Meanwhile, I'll stick to a good diet and excercise program... Seems to be working so far. I was mistaken for a twenty-something the other day.


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sophrosyne
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posted 28 May 2003 02:59 PM      Profile for sophrosyne     Send New Private Message      Edit/Delete Post  Reply With Quote 
I think this topic certainly belongs in the feminism section.

After all, the Western medical system has a long and not-so-proud tradition of marginalizing women's health issues, and not conducting thorough-enough testing to verify that drugs treatments etc. have the same effect on females as they do males.

This "sudden" discovery that hormone treatments might be bad for women is not surprising in this light. Not enough research is devoted to researching women's health issues.


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skdadl
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posted 28 May 2003 03:00 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
We should probably have a thread somewhere -- you guys tell me where: somewhere semi-jokey -- where we can define the poles:

The serious depressives (those who are convinced that we're all going to die, so why don't we all die as soon as poss) argue with the serious fountain-of-youth types (those who think they're going to be playing tennis at ninety and really like the idea of plastic surgery).

I am convinced that the last battle on earth will be fought between those two groups. (You are all aware, of course, of how often "the last battle on earth" has been re-cast between two oversimplified poles of all sorts?)

Put me in camp 1. I hardly expect to live out the day. I like getting older. I have never wanted to be younger. I try to look as awful as I can.

lagatta: choose your weapons!

(And recognize that your allies -- in the anglo-Canadian media, anyway, are Margaret Wente and Barbara Amiel. )


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lagatta
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posted 28 May 2003 03:04 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
I don't take HRT. I am very suspicious of overmedicalisation. But I do think getting older is the pits. I'd rather be dead than asexual.
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Timebandit
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posted 28 May 2003 03:04 PM      Profile for Timebandit     Send New Private Message      Edit/Delete Post  Reply With Quote 
Well, I very well might be playing tennis at 90, if it strikes my fancy. Why not? Everybody told me I wouldn't be jogging at 8 mos pregnant, and I did that. But I'll be doing it without cosmetic surgery and "youth" drugs.

At the very least, I hope to be driving two or three generations of progeny batty.

And I think those who try to achieve that aim with surgery and drugs are going to die off a lot sooner than me.


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Timebandit
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posted 28 May 2003 03:06 PM      Profile for Timebandit     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
But I do think getting older is the pits. I'd rather be dead than asexual.

lagatta, getting older doesn't mean becoming asexual. I'd like to introduce you to my Nana. She's 87 and still dating. A widow since her early 60s, she's always had at least one man on a string. She's amazing.


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Alix
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posted 28 May 2003 03:07 PM      Profile for Alix     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Originally posted by lagatta:
I don't take HRT. I am very suspicious of overmedicalisation. But I do think getting older is the pits. I'd rather be dead than asexual.

I have one grandmother that would take you to task over the idea that getting older means you're asexual. I still remember the day I called her when she was making "Better-Than-Sex Cake" and she told me "It's isn't really, but we call it that anyway."

She's in her early eighties, and I strongly, strongly suspect sex is not a thing of the past for her.


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lagatta
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posted 28 May 2003 03:12 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
Bully for them.

Where do they find guys? There was a huge spate of early mortality - most of it smoking related, among guy friends just a bit older than me in recent years.

Of course, some could be lesbians, but Zoot's relative seems het.

I was also referring to certain (ahem) medical phenomena that affect both men and women. Need I be more explicit?


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skdadl
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posted 28 May 2003 04:12 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
lagatta, demographers tell us that you and I had the misfortune to belong to the cohort (I think we are within ten yrs of each other, yes?) that not only had a peculiar shortage of males but also followed a much smaller cohort (those born in the late Depression and early war years), thus cutting back severely any female's chances of finding a mate -- while simultaneously encouraging the males to remain Peter Pans as long as poss (seller's market, and they were the sellers).

I think younger women find our pickle hard to relate to.

Not that a shortage of males is bothering moi all that much lately. Gosh, it is a dirty job, but someone's got to do it: I shall shortly take on the task of defending asexuality. Back soon.


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Timebandit
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posted 28 May 2003 04:16 PM      Profile for Timebandit     Send New Private Message      Edit/Delete Post  Reply With Quote 
Lagatta, my grandmother has taken to dating younger men... She tells me the older ones can't keep up.
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clersal
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posted 28 May 2003 05:45 PM      Profile for clersal     Send New Private Message      Edit/Delete Post  Reply With Quote 

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Trisha
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posted 28 May 2003 06:23 PM      Profile for Trisha     Send New Private Message      Edit/Delete Post  Reply With Quote 
Women don't necessarily lose their sex drive as they get older and don't need pills for the small inconvenience that does develop. A simple cream takes good care of that problem. Again, women losing sex drive is mainly a man's fear or viewpoint.

I see no reason why a woman shouldn't date younger men. Often they're the only ones that can keep up with us.


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lagatta
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posted 28 May 2003 06:34 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
Men also have problems 'down there'. One thing nature seems equitable about.

Have no desire to go through the many plastic surgeries to raise and tighten everything to find a younger men, and middle-aged and older women who've done that (thinking of a wealthy aunt of mine, and no, she has never given me or anyone else in the family a cent) just look like older women who've had stuff done...

She did get a 'younger' man (must be almost 70 by now) but as you might suspect, he's a bit of a gold-digger.


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skdadl
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posted 28 May 2003 07:02 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
Perhaps I'm just an oddity, but again I pose the question: why sex?

I mean, honestly? Am I just odd?


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Trisha
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posted 28 May 2003 07:52 PM      Profile for Trisha     Send New Private Message      Edit/Delete Post  Reply With Quote 
I've never been into sex just for the sake of sex and have found that the lack of it doesn't bother me unless I'm highly attracted to someone and having a relationship with them. I think the entire focus of the importance of sex is highly overrated. It's great, sure, but hardly a life-or-death issue.
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muggetywumpus
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posted 29 May 2003 02:52 PM      Profile for muggetywumpus        Edit/Delete Post  Reply With Quote 
This article follows revelationa from a few months ago that HRT does not protect against postmenopausal increased risk of heart disease and stroke either, quite the contrary:

quote:
The estrogen and progestin component of the Women's Health Initiative, which included over 16,000 women, compared two groups of healthy women (no prior history of heart disease), one using estrogen with progestin and one taking a placebo. In this study, combined estrogen and progestin was associated with a 22 percent increased risk of cardiovascular disease. The incidence of heart attacks increased 29 percent among women taking estrogen and progestin, as compared to the group of women on placebo (2). These effects became apparent after an average of 5.2 years of follow-up.

http://www.cancer.gov/newscenter/estrogenplus

Hot flashes are the pits, especially if you're working outside the home. And of course there are other things that happen during menopause, even though it's not an illness. So far Black Cohosh seems to be one of the herbals that are somewhat effective and don't have any horrendous side effects.

http://healthlink.mcw.edu/article/989697316.html


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Rebecca West
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posted 29 May 2003 04:41 PM      Profile for Rebecca West     Send New Private Message      Edit/Delete Post  Reply With Quote 
Friends of mine have had considerable success with black cohosh, and they didn't have to take it for years and years. I imagine the results vary from woman to woman, and I do understand that for some women the effects of menopause are so severe as to be almost debilitating. Perhaps where it is an immediate quality of life issue, and HRT is the only thing that will provide relief, it's worth the risk at the lowest dose possible for the shortest period of time possible.

As for sexual desire and aging, I've noticed changes, certainly, as I've grown older (I'm in my 40s now). Nowadays, my desires are more cyclical, with a definite ebb and flow at different times of the month. That doesn't mean that at low ebb I don't want any sexual contact - it just takes a little longer to get things going, or I may not orgasm as quickly, or at all for that matter.

When I was younger, I was good to go all the time and it all seemed so effortless. That's a breeding thing, I imagine. But I have to say that on the whole, sex is far more enjoyable now than it was when I was in my 20s and early 30s. It's just different.


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skdadl
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posted 29 May 2003 04:56 PM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
What I have never understood about any kind of therapy for the effects of menopause (and I also take them very seriously: I know that some women have to have relief) is how you come off the therapy. What happens when you stop whichever medication it is? Won't the symptoms simply show up then, delayed?

That's an honest question. I've always wondered.

I ended up not having to argue with anyone about HRT because, right when I hit menopause, I had a medical situation that ruled it out. I probably was experiencing some mild effects, like night sweats, especially -- ok, sweats, generally -- but at the time, I was so worried about other things that my sweating, which was minor, really seemed minor.


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Alix
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posted 29 May 2003 05:07 PM      Profile for Alix     Send New Private Message      Edit/Delete Post  Reply With Quote 
Yes, to the best of my knowledge, when you come off the hormone therapy, you then go through menopause. Some women take them (took them) thinking that they will continue to take hormones for the rest of their lives.
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lagatta
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posted 29 May 2003 06:09 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
I have an aunt, over 80, who is still taking the stuff - not just a low dosage, but enough to keep her having her period. But then this aunt is, as I've said, a plastic surgery junkie. And no, she doesn't look 35. Perhaps she looks a bit younger than her age, but that is because she is wealthy and can afford good food etc - and a toyboy who is now pushing 70 .

Indeed, many serious medical conditions USUALLY make menopausal complaints fade into the background. But I do have friends who are really debilitated by them, and the herbal stuff doesn't work.

I still think a sex life, of sorts, is essential to being fully human, unless one has deliberately waived it for religious or ethical reasons. Don't mean meaningless recreational sex, unless that is what you want. Not the slightest bit interested. But I went for years without really touching another human being, and felt like a dried -out carapace.


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Timebandit
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posted 29 May 2003 06:33 PM      Profile for Timebandit     Send New Private Message      Edit/Delete Post  Reply With Quote 
Coincidentally, I came across this article today...

http://www.salon.com/mwt/feature/2003/05/29/juska/index.html

If you're not a Salon subscriber, you have to look at an ad to get their "day pass" so you can read the whole article. Sorry for that, but the article is right in line with the discussion.

[ 29 May 2003: Message edited by: Zoot Capri ]


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lagatta
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posted 29 May 2003 07:04 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
Not really interested in that type of person, male or female, old or young. Mindless consumption, before food or drink, now fucking. The opposite number of aestheticism and wilful celibacy. Nun or whore.
From: Se non ora, quando? | Registered: Apr 2002  |  IP: Logged
Timebandit
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posted 29 May 2003 07:31 PM      Profile for Timebandit     Send New Private Message      Edit/Delete Post  Reply With Quote 
Well, it may well be the opposite of aeseticism and celibacy as a choice, but I didn't read into it the negative connotation of whore versus nun.

The point that struck me was that Juska is an older woman choosing to be an active sexual being when our culture normally relegates women of that age, especially unmarried ones, to the asexuality that you seemed very much against in your earlier post. Further to that, she said something to the effect of at that stage of life, sex was different in many ways than it is for younger women.

Whether she's taking HRT, though, is anybody's guess.


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lagatta
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posted 29 May 2003 07:48 PM      Profile for lagatta     Send New Private Message      Edit/Delete Post  Reply With Quote 
Yes, but she was talking about mindless, soulless consumption of sex. When men do that, we call them 'collectors'. Her own business, but hardly a model. That is why I was talking about nun or whore.
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skdadl
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posted 30 May 2003 11:04 AM      Profile for skdadl     Send New Private Message      Edit/Delete Post  Reply With Quote 
I thought that article was great fun. And I think Juska sounds wonderful.

But lagatta, she says it isn't "casual" sex to her at all, and obviously the three guys she's now settled on mean something to her. I think I also would have had trouble setting up the project the way she did -- but where she is now sounds terrific. Maybe not for me -- but she sounds terrific.

This I think I understand:

quote:

Juska turns around and looks them both up and down, before she remembers my question. "Oh wait, I'm sorry, about soul mates?" She crosses, then recrosses her legs, smiles. "Look, I'm in a much different place than you are at your age. Maybe it's an evolutionary thing. I've done marriage and kids. I'm not into nesting. I don't have much time left. And I have these lovely interactions with these men -- maybe it's because for me, and for other people my age, there's a certain poignancy and sweetness that comes from being so close to the end."

I dunno. I think she puts that well. She is obviously an unusual person -- what struck me about the article from early on is that it seems so literary itself, and it treats her as more of a literary figure than the subjects of news articles are usually treated. I mean, we watch her m.o. She has the eye and the spirit of a novelist -- very sharp, witty, perhaps too detached for some people, but how else does a writer home in on deep truths? Her dialogue throughout sparkles. She's not me, but good for her.


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Rebecca West
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posted 30 May 2003 12:32 PM      Profile for Rebecca West     Send New Private Message      Edit/Delete Post  Reply With Quote 
It seems she's just trying out another way of being with people, men in this case. Some people experiement with casual sexual relationships when they're young, some when they're older, after marriage and children, some are never interested in that sort of thing. The thing that could possibly be wrong is continuing on a course that doesn't make you happy in any way, or is destructive to others.

Good for her for knowing what she wants and enjoying herself fully, without guilt or conformity to external ideas of how an older woman should or shouldn't be sexual.


From: London , Ontario - homogeneous maximus | Registered: Nov 2001  |  IP: Logged

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